Intraoperative force and electrocochleography measurements in an animal model of cochlear implantation

J Lo; C Bester; A Collins; C Newbold; A Hampson; S Chambers; H Eastwood; S O'Leary

Journal article

Intraoperative force and electrocochleography measurements in an animal model of cochlear implantation

J Lo, C Bester, A Collins, C Newbold, A Hampson, S Chambers, H Eastwood, S O'Leary

Hearing Research | ELSEVIER SCIENCE BV | Published : 2018

DOI: 10.1016/j.heares.2017.11.001

Abstract

To preserve residual hearing, techniques for monitoring and reducing the effects of trauma during cochlear implant surgery are being developed. This study examines the relationships between intraoperative recordings (electrode insertion force and electrocochleography), trauma, and hearing loss after cochlear implantation. The study also evaluated the efficacy of intravenous steroids for reducing hearing loss after implantation. Thirty-two normal-hearing guinea pigs were randomly implanted with electrode arrays of differing stiffness (‘hard’ or ‘soft’). These arrays used an intracochlear electrode to record electrode insertion force and electrocochleography responses to a multi-frequency acou..

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University of Melbourne Researchers

Christo Bester Author

Aaron Collins Author

Carrie Newbold Author

Amy Hampson Author

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PRACTITIONER FELLOWSHIP - PROF STEPHEN O'LEARY

Prof O'Leary is an ear, nose and throat surgeon determining how best to prevent hearing loss during surgery.

SURGICAL APPROACHES TO IMPROVING EAR HEALTH AND HEARING

My vision is to advance ear and hearing health all Australians across three areas. The first is to ensure that patients receiving hearing-re..

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Funding Acknowledgements

The first author is a recipient of the Hugh Noel Puckle Scholarship and an Australian Postgraduate Award. SOL is supported by a Practitioner Fellowship from the National Health and Research Council (Australia), GNT0628679 and GNT1078673. The authors wish to thank the following: Helen Feng for manufacturing the electrode arrays, Sjaak Klis (University Hospital Utrecht, Netherlands) for providing the gold ball recording electrodes, Hanif Miah (Cochlear Limited) for assistance with Instron recordings, Dimitra Stathopoulos for the expoxy cochlear model and Dr Luke Campbell for designing and programming the system for extracochlear electrocochleography recordings.